Hormone Drugs May Disarm Coronavirus Spike Protein and Stop COVID-19 Disease Progression

A new Penn Medicine study shows how anti-androgen drugs disrupt key receptors required for viral invasion of cells. Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press‘s iScience.